PANTHER Gene Information   
Gene Symbol(s): ESR1
Organism: Ornithorhynchus anatinus
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Gene Name: Estrogen receptor
Gene ID: ENSOANG00000040685.1
Protein ID: A0A6I8P895
Persistent Id: PTN008485815
Alternate Ids:
A0A6I8P895(Synonym) ENSOANP00000049009(Ensembl_PRO)
ENSOANG00000040685(Ensembl) ENSOANT00000074081(Ensembl_TRS)
A0A6I8P895_ORNAN(UniProtKB-ID)
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PANTHER Classification
PANTHER Family: KNIRPS-RELATED PROTEIN-RELATED (PTHR48092)
PANTHER Subfamily: ESTROGEN RECEPTOR (PTHR48092:SF16)  
PANTHER GO-slim Molecular Function: RNA polymerase II cis-regulatory region sequence-specific DNA binding
DNA-binding transcription factor activity, RNA polymerase II-specific
signaling receptor activity
PANTHER GO-slim Biological Process: regulation of transcription by RNA polymerase II
PANTHER GO-slim Cellular Component: chromatin
nucleus
PANTHER protein class: C4 zinc finger nuclear receptor
Pathway Categories: No pathway information available
GENE ONTOLOGY DATABASE ANNOTATIONS      Click to Expand...
GO MF Complete: protein kinase binding, zinc ion binding, identical protein binding, estrogen response element binding, nuclear estrogen receptor activity, RNA polymerase II cis-regulatory region sequence-specific DNA binding, DNA-binding transcription activator activity, RNA polymerase II-specific, sequence-specific DNA binding, chromatin binding, steroid binding, beta-catenin binding, transcription coactivator binding, transcription corepressor binding, transcription coregulator binding, DNA binding, nuclear receptor activity, metal ion binding, TFIIB-class transcription factor binding, TBP-class protein binding, nuclear estrogen receptor binding, sequence-specific double-stranded DNA binding, enzyme binding, ATPase binding, 14-3-3 protein binding
GO BP Complete: vagina development, response to estrogen, male gonad development, negative regulation of miRNA transcription, regulation of epithelial cell apoptotic process, mammary gland branching involved in pregnancy, transcription by RNA polymerase II, epithelial cell development, prostate epithelial cord arborization involved in prostate glandular acinus morphogenesis, negative regulation of canonical NF-kappaB signal transduction, positive regulation of transcription by RNA polymerase II, steroid hormone receptor signaling pathway, regulation of branching involved in prostate gland morphogenesis, prostate epithelial cord elongation, negative regulation of transcription by RNA polymerase II, fibroblast proliferation, RNA polymerase II preinitiation complex assembly, cellular response to estradiol stimulus, stem cell differentiation, mammary gland alveolus development, antral ovarian follicle growth, positive regulation of DNA-templated transcription, positive regulation of fibroblast proliferation, estrogen receptor signaling pathway, epithelial cell proliferation involved in mammary gland duct elongation, regulation of toll-like receptor signaling pathway, regulation of DNA-templated transcription, cellular response to estrogen stimulus, regulation of transcription by RNA polymerase II, negative regulation of gene expression, androgen metabolic process, protein localization to chromatin, response to estradiol, regulation of inflammatory response
GO CC Complete: nucleus, transcription regulator complex, euchromatin, cytoplasm, protein-containing complex, chromatin, plasma membrane
REACTOME DATABASE ANNOTATIONS   Click to Expand...
Reactome Pathways: -

Orthologs