PANTHER Gene Information   
Gene Symbol(s): esr1
Organism: Xenopus tropicalis
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Gene Name: Estrogen receptor
Gene ID: XB-GENE-482193
Protein ID: Q6W5G9
Persistent Id: PTN000639425
Alternate Ids:
Q6W5G9_XENTR(UniProtKB-ID) 35396533(GI)
AY310902(EMBL) NP_988866(refSeq)
Q6W5G9(Synonym) 394461(GeneID)
AAQ84780(EMBL-CDS)
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PANTHER Classification
PANTHER Family: KNIRPS-RELATED PROTEIN-RELATED (PTHR48092)
PANTHER Subfamily: ESTROGEN RECEPTOR (PTHR48092:SF16)  
PANTHER GO-slim Molecular Function: RNA polymerase II cis-regulatory region sequence-specific DNA binding
DNA-binding transcription factor activity, RNA polymerase II-specific
signaling receptor activity
PANTHER GO-slim Biological Process: regulation of transcription by RNA polymerase II
PANTHER GO-slim Cellular Component: chromatin
nucleus
PANTHER protein class: C4 zinc finger nuclear receptor
Pathway Categories: No pathway information available
GENE ONTOLOGY DATABASE ANNOTATIONS      Click to Expand...
GO MF Complete: DNA binding, zinc ion binding, nuclear receptor activity, estrogen response element binding, metal ion binding, nuclear estrogen receptor activity, sequence-specific DNA binding, steroid binding
GO BP Complete: regulation of DNA-templated transcription, estrogen receptor signaling pathway, steroid hormone receptor signaling pathway, cellular response to estrogen stimulus, regulation of transcription by RNA polymerase II
GO CC Complete: nucleus, chromatin
REACTOME DATABASE ANNOTATIONS   Click to Expand...
Reactome Pathways: Signal Transduction, TFAP2 (AP-2) family regulates transcription of growth factors and their receptors, Gene expression (Transcription), Estrogen-dependent gene expression, Metabolism of proteins, Generic Transcription Pathway, PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling, Post-translational protein modification, SUMO E3 ligases SUMOylate target proteins, Transcriptional regulation by the AP-2 (TFAP2) family of transcription factors, Negative regulation of the PI3K/AKT network, Intracellular signaling by second messengers, SUMOylation of intracellular receptors, Ovarian tumor domain proteases, Nuclear signaling by ERBB4, ESR-mediated signaling, Signaling by ERBB4, Deubiquitination, Extra-nuclear estrogen signaling, Nuclear Receptor transcription pathway, PIP3 activates AKT signaling, SUMOylation, RNA Polymerase II Transcription, Signaling by Receptor Tyrosine Kinases, Signaling by Nuclear Receptors

Orthologs