PANTHER Gene Information   
Gene Symbol(s): Gnb5
Organism: Mus musculus
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Gene Name: Guanine nucleotide-binding protein subunit beta-5
Gene ID: MGI:101848
Protein ID: P62881
Persistent Id: PTN000457506
Alternate Ids:
O35354(AltAccession) Gnb5(Symbol)
U69145(EMBL) GNB5(Synonym)
166235373(GI) AAC52886(EMBL-CDS)
ENSMUSG00000032192(Ensembl) GNB5_MOUSE(UniProtKB-ID)
MGI:101848(MGI) 14697(GeneID)
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PANTHER Classification
PANTHER Family: GUANINE NUCLEOTIDE-BINDING PROTEIN BETA G PROTEIN BETA (PTHR19850)
PANTHER Subfamily: GUANINE NUCLEOTIDE-BINDING PROTEIN SUBUNIT BETA-5 (PTHR19850:SF36)  
PANTHER GO-slim Molecular Function: signaling receptor complex adaptor activity
PANTHER GO-slim Biological Process: G protein-coupled receptor signaling pathway
dopamine receptor signaling pathway
PANTHER GO-slim Cellular Component: plasma membrane protein complex
extrinsic component of membrane
cytoplasm
catalytic complex
cytoplasmic side of plasma membrane
PANTHER protein class: heterotrimeric G-protein
Pathway Categories: Beta3 adrenergic receptor signaling pathway
   G-Protein
Thyrotropin-releasing hormone receptor signaling pathway
   G-Protein
Histamine H1 receptor mediated signaling pathway
   G-Protein
5HT1 type receptor mediated signaling pathway
   G-protein
5HT4 type receptor mediated signaling pathway
   G-protein
Muscarinic acetylcholine receptor 1 and 3 signaling pathway
   Gq-protein
Gonadotropin-releasing hormone receptor pathway
   Gbeta
Beta1 adrenergic receptor signaling pathway
   G-Protein
PI3 kinase pathway
   G protein, beta and gamma subunit
5HT2 type receptor mediated signaling pathway
   G-protein
Enkephalin release
   Gi-protein
Opioid proenkephalin pathway
   G-protein
Enkephalin release
   Gs-protein
Angiotensin II-stimulated signaling through G proteins and beta-arrestin
   G-protein, beta subunit
Opioid prodynorphin pathway
   G-protein
Heterotrimeric G-protein signaling pathway-rod outer segment phototransduction
   G protein, beta subunit 5L
Beta2 adrenergic receptor signaling pathway
   G-Protein
Histamine H2 receptor mediated signaling pathway
   G-Protein
Opioid proopiomelanocortin pathway
   G-protein
Muscarinic acetylcholine receptor 2 and 4 signaling pathway
   Gi-protein
Metabotropic glutamate receptor group III pathway
   Gi-protein
Cortocotropin releasing factor receptor signaling pathway
   G-Protein
Metabotropic glutamate receptor group II pathway
   G-protein
Oxytocin receptor mediated signaling pathway
   G-Protein
GENE ONTOLOGY DATABASE ANNOTATIONS      Click to Expand...
GO MF Complete: protein binding, GTPase activator activity, protein-folding chaperone binding, G-protein gamma-subunit binding, GTPase activating protein binding, signaling receptor complex adaptor activity
GO BP Complete: light adaption, G protein-coupled receptor signaling pathway, signal transduction, negative regulation of voltage-gated calcium channel activity, G protein-coupled dopamine receptor signaling pathway, dark adaptation, positive regulation of GTPase activity
GO CC Complete: presynaptic membrane, myelin sheath, synapse, plasma membrane, nucleus, dendrite, presynapse, heterotrimeric G-protein complex, cell tip, cytoplasm, postsynaptic membrane, membrane, cell body, parallel fiber to Purkinje cell synapse, cytosol, protein-containing complex
REACTOME DATABASE ANNOTATIONS   Click to Expand...
Reactome Pathways: G protein gated Potassium channels, Regulation of insulin secretion, G alpha (q) signalling events, GPCR downstream signalling, Integration of energy metabolism, Vasopressin regulates renal water homeostasis via Aquaporins, Signaling by Nuclear Receptors, Inhibition of voltage gated Ca2+ channels via Gbeta/gamma subunits, Aquaporin-mediated transport, G-protein beta:gamma signalling, Protein folding, Thromboxane signalling through TP receptor, Adrenaline,noradrenaline inhibits insulin secretion, Presynaptic function of Kainate receptors, G beta:gamma signalling through PLC beta, Activation of kainate receptors upon glutamate binding, Glucagon-type ligand receptors, Opioid Signalling, Inwardly rectifying K+ channels, Signaling by WNT, G alpha (12/13) signalling events, Visual phototransduction, Signal Transduction, Beta-catenin independent WNT signaling, Platelet homeostasis, Glucagon-like Peptide-1 (GLP1) regulates insulin secretion, GPER1 signaling, G beta:gamma signalling through BTK, Potassium Channels, Sensory Perception, G alpha (z) signalling events, GPCR ligand binding, Transport of small molecules, G alpha (i) signalling events, GABA receptor activation, Class B/2 (Secretin family receptors), G alpha (s) signalling events, GABA B receptor activation, Signal amplification, ADP signalling through P2Y purinoceptor 1, Transmission across Chemical Synapses, Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding, ESR-mediated signaling, Extra-nuclear estrogen signaling, Neuronal System, Chaperonin-mediated protein folding, Signaling by GPCR, Activation of G protein gated Potassium channels, Neurotransmitter receptors and postsynaptic signal transmission, G beta:gamma signalling through PI3Kgamma, The phototransduction cascade, ADP signalling through P2Y purinoceptor 12, Activation of GABAB receptors, Platelet activation, signaling and aggregation, Inactivation, recovery and regulation of the phototransduction cascade, Hemostasis, Thrombin signalling through proteinase activated receptors (PARs), Metabolism, G-protein activation, G beta:gamma signalling through CDC42, Prostacyclin signalling through prostacyclin receptor, Ca2+ pathway, Metabolism of proteins

Orthologs