Pathway Component Details
| Name: | Guanine nucleotide exchange factor VAV (vav) |
| Definition: | vav is a guanine nucleotide exchange factor for the small GTPase, Rac, which is activates upon its own recruitment to phosporylated BLNK. B cells deficient in vav-1, -2, or -3 show defects in development and response to antigen. |
| Category ID: | P00368 |
| Synonyms: | |
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| Downstream: | |
| Number Families/Subfamilies: | 3 |
| Number of Associated Sequences: | 17 |
| GO Molecular Function: |
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| GO Biological Process: |
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| GO Cellular Component: |
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| PANTHER protein class: |
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| References: |
Sequence Association
| Panther Subfamily | Associated Sequence | Definition | Confidence Code | Evidence |
| PTHR45818:SF1 | A0A5F8A629 | Vav guanine nucleotide exchange factor 3 | ISS | PubMed:14623913 |
| A0A8I3NC73 | Vav guanine nucleotide exchange factor 3 | ISS | PubMed:14623913 | |
| A0A8I5ZPB5 | Vav guanine nucleotide exchange factor 3 | ISS | PubMed:14623913 | |
| E1BBD2 | Vav guanine nucleotide exchange factor 3 | ISS | PubMed:14623913 | |
| F7EJL2 | Vav guanine nucleotide exchange factor 3 | ISS | PubMed:14623913 | |
| H2PZI8 | Vav guanine nucleotide exchange factor 3 | ISS | PubMed:14623913 | |
| Q9R0C8 | Guanine nucleotide exchange factor VAV3 | IGI | PubMed:14623913 | |
| Q9UKW4 | Guanine nucleotide exchange factor VAV3 | IGI | PubMed:14623913 | |
| PTHR45818:SF2 | A0A8I3NA65 | Vav guanine nucleotide exchange factor 1 | ISS | PubMed:10661401 |
| A0A8I3NA65 | Vav guanine nucleotide exchange factor 1 | ISS | PubMed:14623913 | |
| H2QF58 | Vav guanine nucleotide exchange factor 1 | ISS | PubMed:10661401 | |
| H2QF58 | Vav guanine nucleotide exchange factor 1 | ISS | PubMed:14623913 | |
| P15498 | Proto-oncogene vav | IGI | PubMed:10661401 | |
| P15498 | Proto-oncogene vav | IGI | PubMed:14623913 | |
| P27870 | Proto-oncogene vav | IGI | PubMed:10661401 | |
| P27870 | Proto-oncogene vav | IGI | PubMed:14623913 | |
| PTHR45818:SF4 | A0A2I3TV44 | Vav guanine nucleotide exchange factor 2 | ISS | PubMed:14623913 |
| D3ZYG0 | Vav guanine nucleotide exchange factor 2 | ISS | PubMed:14623913 | |
| I2CU78 | Guanine nucleotide exchange factor VAV2 isoform 1 | ISS | PubMed:14623913 | |
| P52735 | Guanine nucleotide exchange factor VAV2 | IGI | PubMed:14623913 | |
| Q60992 | Guanine nucleotide exchange factor VAV2 | IGI | PubMed:14623913 |
