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Gene Symbol(s):
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Vav1
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| Organism: |
Mus musculus |
| View Gene in Tree |
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| Gene Name: |
Proto-oncogene vav
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| Gene ID: |
MGI:98923
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| Protein ID: |
P27870
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| Persistent Id: |
PTN000518545 |
| Alternate Ids: |
| NM_011691(refSeq) |
MGI:98923(MGI) |
| p95vav(Synonym) |
202344(GI) |
| VAV_MOUSE(UniProtKB-ID) |
Q8BTV7(AltAccession) |
| ENSMUSG00000034116(Ensembl) |
ENSMUSP00000005889(Ensembl_PRO) |
| AK088586(EMBL) |
AAA63402(EMBL-CDS) |
| Vav1(Symbol) |
ENSMUST00000005889(Ensembl_TRS) |
22324(GeneID) |
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Show All
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| GO MF Complete: |
phosphotyrosine residue binding, protein binding, phosphorylation-dependent protein binding, metal ion binding, guanyl-nucleotide exchange factor activity
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| GO BP Complete: |
G protein-coupled receptor signaling pathway, T cell costimulation, small GTPase-mediated signal transduction, regulation of cell size, T cell activation, natural killer cell mediated cytotoxicity, positive regulation of cell adhesion, positive regulation of GTPase activity, positive regulation of natural killer cell mediated cytotoxicity, T cell differentiation, reactive oxygen species metabolic process, integrin-mediated signaling pathway, immune response, immune response-regulating cell surface receptor signaling pathway, regulation of GTPase activity, phagocytosis, neutrophil chemotaxis, natural killer cell activation, cell migration, intracellular signal transduction, positive regulation of phosphatidylinositol 3-kinase/protein kinase B signal transduction
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| GO CC Complete: |
cell-cell junction, cytoplasm, cytosol
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| Reactome Pathways: |
Immune System, Signaling by Receptor Tyrosine Kinases, Negative regulation of the PI3K/AKT network, RHOG GTPase cycle, Cell death signalling via NRAGE, NRIF and NADE, GPCR downstream signalling, VEGFA-VEGFR2 Pathway, VEGFR2 mediated vascular permeability, Drug ADME, FCERI mediated Ca+2 mobilization, PIP3 activates AKT signaling, RHOA GTPase cycle, Signaling by the B Cell Receptor (BCR), Signaling by Erythropoietin, RHO GTPase cycle, p75 NTR receptor-mediated signalling, NRAGE signals death through JNK, Erythropoietin activates RAS, RAC2 GTPase cycle, Signaling by GPCR, RAC1 GTPase cycle, Death Receptor Signaling, Signaling by VEGF, Signaling by Rho GTPases, G alpha (12/13) signalling events, FCERI mediated MAPK activation, Innate Immune System, Signal Transduction, Antigen activates B Cell Receptor (BCR) leading to generation of second messengers, Intracellular signaling by second messengers, Fcgamma receptor (FCGR) dependent phagocytosis, Interleukin-3, Interleukin-5 and GM-CSF signaling, CD28 co-stimulation, PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling, Regulation of actin dynamics for phagocytic cup formation, CD28 dependent Vav1 pathway, Costimulation by the CD28 family, GPVI-mediated activation cascade, Azathioprine ADME, Signaling by SCF-KIT, Platelet activation, signaling and aggregation, Fc epsilon receptor (FCERI) signaling, Signaling by Rho GTPases, Miro GTPases and RHOBTB3, Hemostasis, Signaling by Interleukins, Cytokine Signaling in Immune system, Regulation of signaling by CBL, Adaptive Immune System
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