PANTHER Gene Information

Gene Symbol(s):

20208860

Organism:

helobdella robusta

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Gene Name:

Uncharacterized protein

Gene ID:

HelroG183126

Protein ID:

T1FJ61

Persistent Id:

PTN002910879

Alternate Ids:

ESN89844(EMBL-CDS)	AMQM01008600(EMBL)
XP_009032074(refSeq)	T1FJ61_HELRO(UniProtKB-ID)
T1FJ61(Synonym)	555686612(GI)
HelroP183126(Ensembl_PRO)	HelroT183126(Ensembl_TRS)
HelroG183126(Ensembl)	20208860(GeneID)
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PANTHER Classification

PANTHER Family:	PROTEIN VAV (PTHR45818)
PANTHER Subfamily:	PROTEIN VAV (PTHR45818:SF3)
PANTHER GO-slim Molecular Function:	guanyl-nucleotide exchange factor activity
PANTHER GO-slim Biological Process:	regulation of GTPase activity
PANTHER GO-slim Cellular Component:	cytoplasm
PANTHER protein class:

Pathway Categories:

PDGF signaling pathway

Guanine nucleotide exchange factor VAV

GENE ONTOLOGY DATABASE ANNOTATIONS

Click to Expand...

GO MF Complete:	metal ion binding, guanyl-nucleotide exchange factor activity
GO BP Complete:	small GTPase-mediated signal transduction, cell migration
GO CC Complete:	cytoplasm

REACTOME DATABASE ANNOTATIONS Click to Expand...

Reactome Pathways:

Orthologs

ID	Organism	Type
HUMAN\|HGNC=12657\|UniProtKB=P15498	Homo sapiens	LDO
PANTR\|Ensembl=ENSPTRG00000010378.4\|UniProtKB=H2QF58	Pan troglodytes	LDO
GORGO\|Ensembl=ENSGGOG00000012257.3\|UniProtKB=G3R994	Gorilla gorilla gorilla	LDO
MACMU\|Ensembl=ENSMMUG00000019314.4\|UniProtKB=A0A1D5RF06	Macaca mulatta	LDO
MOUSE\|MGI=MGI=98923\|UniProtKB=P27870	Mus musculus	LDO
RAT\|RGD=3951\|UniProtKB=P54100	Rattus norvegicus	LDO
BOVIN\|Ensembl=ENSBTAG00000039160\|UniProtKB=Q08DN7	Bos taurus	LDO
PIG\|Ensembl=ENSSSCG00000013553.4\|UniProtKB=A0A286ZQX2	Sus scrofa	LDO
HORSE\|Ensembl=ENSECAG00000014896.3\|UniProtKB=F6VK33	Equus caballus	LDO
FELCA\|Ensembl=ENSFCAG00000005052.6\|UniProtKB=M3W3D5	Felis catus	LDO
CANLF\|Ensembl=ENSCAFG00845008896.1\|UniProtKB=A0A8I3NA65	Canis lupus familiaris	LDO
MONDO\|Ensembl=ENSMODG00000002314.5\|UniProtKB=F7A3L2	Monodelphis domestica	LDO
ORNAN\|Ensembl=ENSOANG00000014870.3\|UniProtKB=F6XXJ5	Ornithorhynchus anatinus	LDO
CHICK\|Ensembl=ENSGALG00010003064.1\|UniProtKB=A0A8V0XJF3	Gallus gallus	LDO
XENLA\|Gene=LOC108705008\|UniProtKB=A0A8J1ME72	Xenopus laevis	O
XENLA\|Gene=vav1.L\|UniProtKB=Q6DCX0	Xenopus laevis	LDO
XENTR\|Xenbase=XB-GENE-6074281\|UniProtKB=A0A6I8SUJ4	Xenopus tropicalis	LDO
ORYLA\|Ensembl=ENSORLG00000009385.2\|UniProtKB=A0A3B3HII6	Oryzias latipes	LDO
LEPOC\|Ensembl=ENSLOCG00000007259.1\|UniProtKB=W5MK78	lepisosteus oculatus	LDO
HUMAN\|HGNC=12659\|UniProtKB=Q9UKW4	Homo sapiens	O
PANTR\|Ensembl=ENSPTRG00000001024.7\|UniProtKB=H2PZI8	Pan troglodytes	O
GORGO\|Ensembl=ENSGGOG00000001895.3\|UniProtKB=G3RM52	Gorilla gorilla gorilla	O
MACMU\|Ensembl=ENSMMUG00000019714.4\|UniProtKB=A0A5F8A629	Macaca mulatta	O
MOUSE\|MGI=MGI=1888518\|UniProtKB=Q9R0C8	Mus musculus	O
RAT\|RGD=1565941\|UniProtKB=A0A8I5ZPB5	Rattus norvegicus	O
BOVIN\|Ensembl=ENSBTAG00000031575.4\|UniProtKB=E1BBD2	Bos taurus	O
HORSE\|Ensembl=ENSECAG00000011099.4\|UniProtKB=A0A3Q2I4K3	Equus caballus	O
FELCA\|Ensembl=ENSFCAG00000001191.6\|UniProtKB=M3VW63	Felis catus	O
CANLF\|Ensembl=ENSCAFG00845009278.1\|UniProtKB=A0A8I3NC73	Canis lupus familiaris	O
MONDO\|Ensembl=ENSMODG00000002796.4\|UniProtKB=F7EJL2	Monodelphis domestica	O
ORNAN\|Ensembl=ENSOANG00000048060.1\|UniProtKB=A0A6I8NA57	Ornithorhynchus anatinus	O
CHICK\|Ensembl=ENSGALG00010011932.1\|UniProtKB=A0A8V0Y6W5	Gallus gallus	O
ANOCA\|Ensembl=ENSACAG00000000782.4\|UniProtKB=A0A803SKV0	Anolis carolinensis	O
XENLA\|Gene=vav3.L\|UniProtKB=A0A8J1MZ10	Xenopus laevis	O
XENLA\|Gene=vav3.S\|UniProtKB=A0A8J1KJL0	Xenopus laevis	O
XENTR\|Xenbase=XB-GENE-6075609\|UniProtKB=F6USI5	Xenopus tropicalis	O
ORYLA\|Ensembl=ENSORLG00000023424.1\|UniProtKB=A0A3B3IIY9	Oryzias latipes	O
DANRE\|Gene=vav3b\|UniProtKB=A0A8M2BAQ7	Danio rerio	O
ORYLA\|Ensembl=ENSORLG00000005788.2\|UniProtKB=A0A3B3I2I2	Oryzias latipes	O
DANRE\|Gene=vav3\|UniProtKB=A0A8M9PGG6	Danio rerio	O
LEPOC\|Ensembl=ENSLOCG00000007934.1\|UniProtKB=W5MMP0	lepisosteus oculatus	O
HUMAN\|HGNC=12658\|UniProtKB=P52735	Homo sapiens	O
PANTR\|Ensembl=ENSPTRG00000021525.7\|UniProtKB=A0A2I3TV44	Pan troglodytes	O
GORGO\|Ensembl=ENSGGOG00000007911.3\|UniProtKB=G3S5N5	Gorilla gorilla gorilla	O
MACMU\|Ensembl=ENSMMUG00000017214.4\|UniProtKB=I2CU78	Macaca mulatta	O
MOUSE\|MGI=MGI=102718\|UniProtKB=Q60992	Mus musculus	O
RAT\|RGD=1306285\|UniProtKB=D3ZYG0	Rattus norvegicus	O
BOVIN\|Ensembl=ENSBTAG00000004511.6\|UniProtKB=A0A3Q1MQP9	Bos taurus	O
PIG\|Ensembl=ENSSSCG00000005743.5\|UniProtKB=A0A287B8N4	Sus scrofa	O
HORSE\|Ensembl=ENSECAG00000015126.4\|UniProtKB=A0A5F5Q0A3	Equus caballus	O
FELCA\|Ensembl=ENSFCAG00000011529.6\|UniProtKB=M3WF96	Felis catus	O
CANLF\|Ensembl=ENSCAFG00845011337.1\|UniProtKB=A0A8I3NEZ8	Canis lupus familiaris	O
MONDO\|Ensembl=ENSMODG00000001674.3\|UniProtKB=F6SQP5	Monodelphis domestica	O
MONDO\|Ensembl=ENSMODG00000013038.4\|UniProtKB=A0A5F8GRN7	Monodelphis domestica	O
ORNAN\|Ensembl=ENSOANG00000002845.4\|UniProtKB=F6U979	Ornithorhynchus anatinus	O
CHICK\|Ensembl=ENSGALG00010028884.1\|UniProtKB=A0A8V1AAH7	Gallus gallus	O
ANOCA\|Ensembl=ENSACAG00000014720.4\|UniProtKB=H9GLK6	Anolis carolinensis	O
XENLA\|Gene=vav2.L\|UniProtKB=A0A8J1LHZ8	Xenopus laevis	O
XENLA\|Gene=vav2.S\|UniProtKB=A0A8J1LL69	Xenopus laevis	O
XENTR\|Gene=vav2\|UniProtKB=A0A8J1IPD9	Xenopus tropicalis	O
ORYLA\|Ensembl=ENSORLG00000012202.2\|UniProtKB=A0A3B3HN02	Oryzias latipes	O
DANRE\|Gene=vav2\|UniProtKB=A0A8M9PUI9	Danio rerio	O
LEPOC\|Ensembl=ENSLOCG00000004506.1\|UniProtKB=W5MAI5	lepisosteus oculatus	O
CIOIN\|Ensembl=ENSCING00000008711.3\|UniProtKB=F6WCA3	Ciona intestinalis	LDO
BRAFL\|Gene=LOC118422080\|UniProtKB=A0A9J7LM76	Branchiostoma floridae	LDO
STRPU\|EnsemblGenome=LOC582602\|UniProtKB=A0A7M7NQJ6	Strongylocentrotus purpuratus	O
STRPU\|EnsemblGenome=LOC582411\|UniProtKB=A0A7M7PMI4	Strongylocentrotus purpuratus	LDO
CAEEL\|WormBase=WBGene00006887\|UniProtKB=Q45FX5	Caenorhabditis elegans	LDO
CAEBR\|Gene_ORFName=CBG16186\|UniProtKB=A8XNX6	Caenorhabditis briggsae	LDO
PRIPA\|EnsemblGenome=WBGene00090011\|UniProtKB=A0A2A6BGJ4	Pristionchus pacificus	LDO
DROME\|FlyBase=FBgn0040068\|UniProtKB=Q9NHV9	Drosophila melanogaster	LDO
ANOGA\|EnsemblGenome=AGAP010292\|UniProtKB=A0A1S4H3M1	Anopheles gambiae	LDO
TRICA\|EnsemblGenome=TC004356\|UniProtKB=A0A139WAM6	Tribolium castaneum	LDO
DAPPU\|EnsemblGenome=DAPPUDRAFT_221220\|UniProtKB=E9FX29	Daphnia pulex	O
DAPPU\|EnsemblGenome=DAPPUDRAFT_323685\|UniProtKB=E9GZG4	Daphnia pulex	LDO
IXOSC\|EnsemblGenome=ISCW014238\|UniProtKB=B7QJT0	Ixodes scapularis	LDO
NEMVE\|EnsemblGenome=NEMVEDRAFT_v1g248472\|UniProtKB=A7T185	Nematostella vectensis	LDO
TRIAD\|EnsemblGenome=TriadG53249\|UniProtKB=B3RNQ4	Trichoplax adhaerens	LDO
MONBE\|EnsemblGenome=MONBRDRAFT_22586\|UniProtKB=A9UR12	Monosiga brevicollis	O
MONBE\|EnsemblGenome=MONBRDRAFT_31066\|UniProtKB=A9UNJ0	Monosiga brevicollis	O
MONBE\|EnsemblGenome=MONBRDRAFT_33960\|UniProtKB=A9V8S2	Monosiga brevicollis	O
MONBE\|EnsemblGenome=MONBRDRAFT_31054\|UniProtKB=A9UR08	Monosiga brevicollis	LDO
PHANO\|EnsemblGenome=SNOG_14232\|UniProtKB=Q0U265	Phaeosphaeria nodorum	LDO
CRYNJ\|EnsemblGenome=CNA05310\|UniProtKB=Q5KNU3	Cryptococcus neoformans	LDO