PANTHER Gene Information

Gene Symbol(s):

vav3

Organism:

Danio rerio

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Gene Name:

Guanine nucleotide exchange factor VAV3

Gene ID:

vav3

Protein ID:

A0A8M9PGG6

Persistent Id:

PTN009186718

Alternate Ids:

1040680897(GI)	XP_021326028(refSeq)
A0A8M9PGG6(Synonym)	A0A8M9PGG6_DANRE(UniProtKB-ID)
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PANTHER Classification

PANTHER Family:	PROTEIN VAV (PTHR45818)
PANTHER Subfamily:	GUANINE NUCLEOTIDE EXCHANGE FACTOR VAV3 (PTHR45818:SF1)
PANTHER GO-slim Molecular Function:	guanyl-nucleotide exchange factor activity
PANTHER GO-slim Biological Process:	cell migration regulation of GTPase activity
PANTHER GO-slim Cellular Component:	cytoplasm plasma membrane
PANTHER protein class:

Pathway Categories:

PDGF signaling pathway

Guanine nucleotide exchange factor VAV

T cell activation

Guanine nucleotide exchange factor VAV

B cell activation

Guanine nucleotide exchange factor VAV

GENE ONTOLOGY DATABASE ANNOTATIONS

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GO MF Complete:	guanyl-nucleotide exchange factor activity
GO BP Complete:	immune response-regulating cell surface receptor signaling pathway, small GTPase-mediated signal transduction, cell migration, positive regulation of phosphatidylinositol 3-kinase/protein kinase B signal transduction
GO CC Complete:	cytoplasm, plasma membrane

REACTOME DATABASE ANNOTATIONS Click to Expand...

Reactome Pathways:

Orthologs

ID	Organism	Type
HUMAN\|HGNC=12659\|UniProtKB=Q9UKW4	Homo sapiens	LDO
PANTR\|Ensembl=ENSPTRG00000001024.7\|UniProtKB=H2PZI8	Pan troglodytes	LDO
GORGO\|Ensembl=ENSGGOG00000001895.3\|UniProtKB=G3RM52	Gorilla gorilla gorilla	LDO
MACMU\|Ensembl=ENSMMUG00000019714.4\|UniProtKB=A0A5F8A629	Macaca mulatta	LDO
MOUSE\|MGI=MGI=1888518\|UniProtKB=Q9R0C8	Mus musculus	LDO
RAT\|RGD=1565941\|UniProtKB=A0A8I5ZPB5	Rattus norvegicus	LDO
BOVIN\|Ensembl=ENSBTAG00000031575.4\|UniProtKB=E1BBD2	Bos taurus	LDO
HORSE\|Ensembl=ENSECAG00000011099.4\|UniProtKB=A0A3Q2I4K3	Equus caballus	LDO
FELCA\|Ensembl=ENSFCAG00000001191.6\|UniProtKB=M3VW63	Felis catus	LDO
CANLF\|Ensembl=ENSCAFG00845009278.1\|UniProtKB=A0A8I3NC73	Canis lupus familiaris	LDO
MONDO\|Ensembl=ENSMODG00000002796.4\|UniProtKB=F7EJL2	Monodelphis domestica	LDO
ORNAN\|Ensembl=ENSOANG00000048060.1\|UniProtKB=A0A6I8NA57	Ornithorhynchus anatinus	LDO
CHICK\|Ensembl=ENSGALG00010011932.1\|UniProtKB=A0A8V0Y6W5	Gallus gallus	LDO
ANOCA\|Ensembl=ENSACAG00000000782.4\|UniProtKB=A0A803SKV0	Anolis carolinensis	LDO
XENLA\|Gene=vav3.L\|UniProtKB=A0A8J1MZ10	Xenopus laevis	O
XENLA\|Gene=vav3.S\|UniProtKB=A0A8J1KJL0	Xenopus laevis	LDO
XENTR\|Xenbase=XB-GENE-6075609\|UniProtKB=F6USI5	Xenopus tropicalis	LDO
ORYLA\|Ensembl=ENSORLG00000005788.2\|UniProtKB=A0A3B3I2I2	Oryzias latipes	LDO
LEPOC\|Ensembl=ENSLOCG00000007934.1\|UniProtKB=W5MMP0	lepisosteus oculatus	LDO
CIOIN\|Ensembl=ENSCING00000008711.3\|UniProtKB=F6WCA3	Ciona intestinalis	O
BRAFL\|Gene=LOC118422080\|UniProtKB=A0A9J7LM76	Branchiostoma floridae	O
STRPU\|EnsemblGenome=LOC582602\|UniProtKB=A0A7M7NQJ6	Strongylocentrotus purpuratus	O
STRPU\|EnsemblGenome=LOC582411\|UniProtKB=A0A7M7PMI4	Strongylocentrotus purpuratus	O
CAEEL\|WormBase=WBGene00006887\|UniProtKB=Q45FX5	Caenorhabditis elegans	O
CAEBR\|Gene_ORFName=CBG16186\|UniProtKB=A8XNX6	Caenorhabditis briggsae	O
PRIPA\|EnsemblGenome=WBGene00090011\|UniProtKB=A0A2A6BGJ4	Pristionchus pacificus	O
DROME\|FlyBase=FBgn0040068\|UniProtKB=Q9NHV9	Drosophila melanogaster	O
ANOGA\|EnsemblGenome=AGAP010292\|UniProtKB=A0A1S4H3M1	Anopheles gambiae	O
TRICA\|EnsemblGenome=TC004356\|UniProtKB=A0A139WAM6	Tribolium castaneum	O
DAPPU\|EnsemblGenome=DAPPUDRAFT_221220\|UniProtKB=E9FX29	Daphnia pulex	O
DAPPU\|EnsemblGenome=DAPPUDRAFT_323685\|UniProtKB=E9GZG4	Daphnia pulex	O
IXOSC\|EnsemblGenome=ISCW014238\|UniProtKB=B7QJT0	Ixodes scapularis	O
HELRO\|EnsemblGenome=HelroG193493\|UniProtKB=T1FV18	helobdella robusta	O
HELRO\|EnsemblGenome=HelroG168451\|UniProtKB=T1F0L8	helobdella robusta	O
HELRO\|EnsemblGenome=HelroG163684\|UniProtKB=T1EUC8	helobdella robusta	O
HELRO\|EnsemblGenome=HelroG183126\|UniProtKB=T1FJ61	helobdella robusta	O
HELRO\|EnsemblGenome=HelroG181812\|UniProtKB=T1FHD1	helobdella robusta	O
NEMVE\|EnsemblGenome=NEMVEDRAFT_v1g248472\|UniProtKB=A7T185	Nematostella vectensis	O
TRIAD\|EnsemblGenome=TriadG53249\|UniProtKB=B3RNQ4	Trichoplax adhaerens	O
MONBE\|EnsemblGenome=MONBRDRAFT_22586\|UniProtKB=A9UR12	Monosiga brevicollis	O
MONBE\|EnsemblGenome=MONBRDRAFT_31066\|UniProtKB=A9UNJ0	Monosiga brevicollis	O
MONBE\|EnsemblGenome=MONBRDRAFT_33960\|UniProtKB=A9V8S2	Monosiga brevicollis	O
MONBE\|EnsemblGenome=MONBRDRAFT_31054\|UniProtKB=A9UR08	Monosiga brevicollis	O
PHANO\|EnsemblGenome=SNOG_14232\|UniProtKB=Q0U265	Phaeosphaeria nodorum	O
CRYNJ\|EnsemblGenome=CNA05310\|UniProtKB=Q5KNU3	Cryptococcus neoformans	O