PANTHER Gene Information   
Gene Symbol(s): SIN3A
Organism: Equus caballus
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Gene Name: SIN3 transcription regulator family member A
Gene ID: ENSECAG00000024605.4
Protein ID: F6QA97
Persistent Id: PTN001389841
Alternate Ids:
F6QA97_HORSE(UniProtKB-ID) ENSECAP00000022189(Ensembl_PRO)
F6QA97(Synonym) ENSECAG00000024605(Ensembl)
ENSECAT00000026583(Ensembl_TRS)
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PANTHER Classification
PANTHER Family: SIN3B-RELATED (PTHR12346)
PANTHER Subfamily: PAIRED AMPHIPATHIC HELIX PROTEIN SIN3A (PTHR12346:SF2)  
PANTHER GO-slim Molecular Function: transcription corepressor activity
PANTHER GO-slim Biological Process: negative regulation of transcription by RNA polymerase II
PANTHER GO-slim Cellular Component: Sin3-type complex
PANTHER protein class: chromatin/chromatin-binding, or -regulatory protein
Pathway Categories: p53 pathway
   Histone deacetylase complex subunit Sin3
Huntington disease
   Histone deacetylase complex subunit Sin3a

GO MF Complete: DNA binding, RNA polymerase II-specific DNA-binding transcription factor binding, transcription corepressor activity, transcription regulator inhibitor activity, chromatin binding
GO BP Complete: negative regulation of protein localization to nucleus, DNA replication, protein localization, regulation of DNA-templated transcription, positive regulation of neuron differentiation, positive regulation of defense response to virus by host, hematopoietic progenitor cell differentiation, negative regulation of circadian rhythm, cerebral cortex neuron differentiation, type I interferon-mediated signaling pathway, negative regulation of transcription by RNA polymerase II, regulation of axon extension, negative regulation of DNA-templated transcription, in utero embryonic development, activation of innate immune response, response to methylglyoxal, cellular response to glucose stimulus, heterochromatin formation, negative regulation of apoptotic process, positive regulation of G2/M transition of mitotic cell cycle
GO CC Complete: nucleus, transcription regulator complex, transcription repressor complex, histone deacetylase complex, kinetochore, chromatin, nucleoplasm, Sin3-type complex
Reactome Pathways: -