PANTHER Gene Information   
Gene Symbol(s): GNB3
Organism: Sus scrofa
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Gene Name: G protein subunit beta 3
Gene ID: ENSSSCG00005028775.1
Protein ID: F1SLU8
Persistent Id: PTN001459517
Alternate Ids:
ENSSSCP00005028013(Ensembl_PRO) F1SLU8(Synonym)
F1SLU8_PIG(UniProtKB-ID) XM_013987271(refSeq)
DQIR01027097(EMBL) ENSSSCT00000000743(Ensembl_TRS)
927132358(GI) ENSSSCG00000000682(Ensembl)
HCZ82572(EMBL-CDS) 100154522(GeneID)
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PANTHER Classification
PANTHER Family: GUANINE NUCLEOTIDE-BINDING PROTEIN BETA G PROTEIN BETA (PTHR19850)
PANTHER Subfamily: GUANINE NUCLEOTIDE-BINDING PROTEIN G(I)_G(S)_G(T) SUBUNIT BETA-3 (PTHR19850:SF31)  
PANTHER GO-slim Molecular Function: signaling receptor complex adaptor activity
PANTHER GO-slim Biological Process: G protein-coupled receptor signaling pathway
PANTHER GO-slim Cellular Component: plasma membrane protein complex
extrinsic component of membrane
cytoplasm
catalytic complex
cytoplasmic side of plasma membrane
PANTHER protein class: heterotrimeric G-protein
Pathway Categories: Beta3 adrenergic receptor signaling pathway
   G-Protein
Wnt signaling pathway
   G protein, beta subunit
Thyrotropin-releasing hormone receptor signaling pathway
   G-Protein
GABA-B receptor II signaling
   G protein, beta subunit
Histamine H1 receptor mediated signaling pathway
   G-Protein
Inflammation mediated by chemokine and cytokine signaling pathway
   G protein, beta and gamma subunit
5HT1 type receptor mediated signaling pathway
   G-protein
5HT4 type receptor mediated signaling pathway
   G-protein
Muscarinic acetylcholine receptor 1 and 3 signaling pathway
   Gq-protein
Dopamine receptor mediated signaling pathway
   G protein, beta subunit
Heterotrimeric G-protein signaling pathway-Gq alpha and Go alpha mediated pathway
   G protein-activated inward rectifying potassium channel
Gonadotropin-releasing hormone receptor pathway
   Gbeta
Endogenous cannabinoid signaling
   G protein, beta subunit
Beta1 adrenergic receptor signaling pathway
   G-Protein
PI3 kinase pathway
   G protein, beta and gamma subunit
5HT2 type receptor mediated signaling pathway
   G-protein
Enkephalin release
   Gi-protein
Opioid proenkephalin pathway
   G-protein
Enkephalin release
   Gs-protein
Angiotensin II-stimulated signaling through G proteins and beta-arrestin
   G-protein, beta subunit
Opioid prodynorphin pathway
   G-protein
Beta2 adrenergic receptor signaling pathway
   G-Protein
Histamine H2 receptor mediated signaling pathway
   G-Protein
Opioid proopiomelanocortin pathway
   G-protein
Muscarinic acetylcholine receptor 2 and 4 signaling pathway
   Gi-protein
Metabotropic glutamate receptor group III pathway
   Gi-protein
Cortocotropin releasing factor receptor signaling pathway
   G-Protein
Metabotropic glutamate receptor group II pathway
   G-protein
Oxytocin receptor mediated signaling pathway
   G-Protein
GENE ONTOLOGY DATABASE ANNOTATIONS      Click to Expand...
GO MF Complete: GTPase binding, signaling receptor complex adaptor activity
GO BP Complete: regulation of glucose metabolic process, G protein-coupled receptor signaling pathway, regulation of hormone metabolic process, regulation of gene expression, regulation of fat cell differentiation, cell volume homeostasis, regulation of triglyceride metabolic process, regulation of cholesterol metabolic process, regulation of phospholipid metabolic process
GO CC Complete: dendrite, heterotrimeric G-protein complex, cytoplasm
REACTOME DATABASE ANNOTATIONS   Click to Expand...
Reactome Pathways: ADP signalling through P2Y purinoceptor 12, Adrenaline,noradrenaline inhibits insulin secretion, Glucagon-type ligand receptors, Signal Transduction, Inwardly rectifying K+ channels, G beta:gamma signalling through PI3Kgamma, G beta:gamma signalling through BTK, Thrombin signalling through proteinase activated receptors (PARs), Metabolism of proteins, Prostacyclin signalling through prostacyclin receptor, G alpha (q) signalling events, Inhibition of voltage gated Ca2+ channels via Gbeta/gamma subunits, Glucagon-like Peptide-1 (GLP1) regulates insulin secretion, Peptide hormone metabolism, Vasopressin regulates renal water homeostasis via Aquaporins, Sensory perception of sweet, bitter, and umami (glutamate) taste, Neurotransmitter receptors and postsynaptic signal transmission, Potassium Channels, Transmission across Chemical Synapses, G-protein beta:gamma signalling, Neuronal System, Signaling by GPCR, GABA B receptor activation, Protein folding, G beta:gamma signalling through PLC beta, Sensory Perception, GPCR ligand binding, Regulation of insulin secretion, G alpha (12/13) signalling events, Incretin synthesis, secretion, and inactivation, Platelet homeostasis, Thromboxane signalling through TP receptor, Beta-catenin independent WNT signaling, Transport of small molecules, Metabolism, GPER1 signaling, Sensory perception of taste, Platelet activation, signaling and aggregation, Activation of G protein gated Potassium channels, G beta:gamma signalling through CDC42, ADP signalling through P2Y purinoceptor 1, G alpha (i) signalling events, Activation of kainate receptors upon glutamate binding, G alpha (z) signalling events, Signaling by WNT, ESR-mediated signaling, Extra-nuclear estrogen signaling, Signal amplification, G alpha (s) signalling events, Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding, GABA receptor activation, Class B/2 (Secretin family receptors), Synthesis, secretion, and inactivation of Glucagon-like Peptide-1 (GLP-1), Opioid Signalling, Integration of energy metabolism, Presynaptic function of Kainate receptors, Hemostasis, Chaperonin-mediated protein folding, G-protein activation, Ca2+ pathway, G protein gated Potassium channels, GPCR downstream signalling, Activation of GABAB receptors, Signaling by Nuclear Receptors, Aquaporin-mediated transport

Orthologs