PANTHER Gene Information   
Gene Symbol(s): Gnb3
Organism: Rattus norvegicus
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Gene Name: Guanine nucleotide-binding protein G(I)_G(S)_G(T) subunit beta-3
Gene ID: 708344
Protein ID: P52287
Persistent Id: PTN000457596
Alternate Ids:
ENSRNOG00000015541(Ensembl) NM_021858(refSeq)
60449(GeneID) AAH86422(EMBL-CDS)
708344(RGD) ENSRNOP00000021480(Ensembl_PRO)
Gnb3(Symbol) GBB3(Synonym)
BC086422(EMBL) ENSRNOT00000021481(Ensembl_TRS)
GBB3_RAT(UniProtKB-ID) 1730216(GI)
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PANTHER Classification
PANTHER Family: GUANINE NUCLEOTIDE-BINDING PROTEIN BETA G PROTEIN BETA (PTHR19850)
PANTHER Subfamily: GUANINE NUCLEOTIDE-BINDING PROTEIN G(I)_G(S)_G(T) SUBUNIT BETA-3 (PTHR19850:SF31)  
PANTHER GO-slim Molecular Function: signaling receptor complex adaptor activity
PANTHER GO-slim Biological Process: G protein-coupled receptor signaling pathway
PANTHER GO-slim Cellular Component: plasma membrane protein complex
extrinsic component of membrane
cytoplasm
catalytic complex
cytoplasmic side of plasma membrane
PANTHER protein class: heterotrimeric G-protein
Pathway Categories: Beta3 adrenergic receptor signaling pathway
   G-Protein
Wnt signaling pathway
   G protein, beta subunit
Thyrotropin-releasing hormone receptor signaling pathway
   G-Protein
GABA-B receptor II signaling
   G protein, beta subunit
Histamine H1 receptor mediated signaling pathway
   G-Protein
Inflammation mediated by chemokine and cytokine signaling pathway
   G protein, beta and gamma subunit
5HT1 type receptor mediated signaling pathway
   G-protein
5HT4 type receptor mediated signaling pathway
   G-protein
Muscarinic acetylcholine receptor 1 and 3 signaling pathway
   Gq-protein
Dopamine receptor mediated signaling pathway
   G protein, beta subunit
Heterotrimeric G-protein signaling pathway-Gq alpha and Go alpha mediated pathway
   G protein-activated inward rectifying potassium channel
Gonadotropin-releasing hormone receptor pathway
   Gbeta
Endogenous cannabinoid signaling
   G protein, beta subunit
Beta1 adrenergic receptor signaling pathway
   G-Protein
PI3 kinase pathway
   G protein, beta and gamma subunit
5HT2 type receptor mediated signaling pathway
   G-protein
Enkephalin release
   Gi-protein
Opioid proenkephalin pathway
   G-protein
Enkephalin release
   Gs-protein
Angiotensin II-stimulated signaling through G proteins and beta-arrestin
   G-protein, beta subunit
Opioid prodynorphin pathway
   G-protein
Beta2 adrenergic receptor signaling pathway
   G-Protein
Histamine H2 receptor mediated signaling pathway
   G-Protein
Opioid proopiomelanocortin pathway
   G-protein
Muscarinic acetylcholine receptor 2 and 4 signaling pathway
   Gi-protein
Metabotropic glutamate receptor group III pathway
   Gi-protein
Cortocotropin releasing factor receptor signaling pathway
   G-Protein
Metabotropic glutamate receptor group II pathway
   G-protein
Oxytocin receptor mediated signaling pathway
   G-Protein
GENE ONTOLOGY DATABASE ANNOTATIONS      Click to Expand...
GO MF Complete: spectrin binding, GTPase binding, signaling receptor complex adaptor activity
GO BP Complete: biological_process, regulation of glucose metabolic process, G protein-coupled receptor signaling pathway, regulation of hormone metabolic process, regulation of gene expression, regulation of fat cell differentiation, cell volume homeostasis, regulation of triglyceride metabolic process, regulation of cholesterol metabolic process, regulation of phospholipid metabolic process
GO CC Complete: dendrite, heterotrimeric G-protein complex, cytoplasm, cell body
REACTOME DATABASE ANNOTATIONS   Click to Expand...
Reactome Pathways: G-protein beta:gamma signalling, Integration of energy metabolism, Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding, Sensory perception of taste, Protein folding, Opioid Signalling, Signaling by WNT, G alpha (q) signalling events, Inhibition of voltage gated Ca2+ channels via Gbeta/gamma subunits, Activation of G protein gated Potassium channels, Vasopressin regulates renal water homeostasis via Aquaporins, ADP signalling through P2Y purinoceptor 12, G beta:gamma signalling through PI3Kgamma, Adrenaline,noradrenaline inhibits insulin secretion, Beta-catenin independent WNT signaling, Metabolism of proteins, Potassium Channels, G-protein activation, Sensory perception of sweet, bitter, and umami (glutamate) taste, Thrombin signalling through proteinase activated receptors (PARs), GPCR downstream signalling, Activation of GABAB receptors, Sensory Perception, Aquaporin-mediated transport, Signaling by GPCR, Ca2+ pathway, GABA B receptor activation, G protein gated Potassium channels, Hemostasis, GPCR ligand binding, Neuronal System, Transmission across Chemical Synapses, Neurotransmitter receptors and postsynaptic signal transmission, Chaperonin-mediated protein folding, G alpha (i) signalling events, Signal amplification, G alpha (z) signalling events, Platelet activation, signaling and aggregation, GABA receptor activation, Inwardly rectifying K+ channels, Class B/2 (Secretin family receptors), Glucagon-like Peptide-1 (GLP1) regulates insulin secretion, Signal Transduction, Glucagon-type ligand receptors, Metabolism, Regulation of insulin secretion, Thromboxane signalling through TP receptor, Transport of small molecules, G beta:gamma signalling through CDC42

Orthologs