PANTHER Gene Information   
Gene Symbol(s): PIK3R1
Organism: Pan troglodytes
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Gene Name: Phosphatidylinositol 3-kinase regulatory subunit alpha
Gene ID: ENSPTRG00000016940.5
Protein ID: A0A2I3SIY1
Persistent Id: PTN000016458
Alternate Ids:
JAA28066(EMBL-CDS) GABE01005134(EMBL)
ENSPTRP00000076964(Ensembl_PRO) XP_517729(refSeq)
A0A2I3SIY1(Synonym) ENSPTRT00000080208(Ensembl_TRS)
694910909(GI) 461836(GeneID)
A0A2I3SIY1_PANTR(UniProtKB-ID) ENSPTRG00000016940(Ensembl)
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PANTHER Classification
PANTHER Family: PHOSPHATIDYLINOSITOL 3-KINASE REGULATORY SUBUNIT (PTHR10155)
PANTHER Subfamily: PHOSPHATIDYLINOSITOL 3-KINASE REGULATORY SUBUNIT ALPHA (PTHR10155:SF3)  
PANTHER GO-slim Molecular Function: kinase regulator activity
PANTHER GO-slim Biological Process: phosphatidylinositol phosphate biosynthetic process
insulin receptor signaling pathway
PANTHER GO-slim Cellular Component: phosphatidylinositol 3-kinase complex
PANTHER protein class: kinase modulator
Pathway Categories: VEGF signaling pathway
   Phosphatidylinositol 3-kinase
PI3 kinase pathway
   p85
T cell activation
   Phosphatidylinositol 3-kinase
Hypoxia response via HIF activation
   Phosphatidylinositol 3-kinase
Insulin/IGF pathway-protein kinase B signaling cascade
   Phosphatidylinositol 3-kinase
Angiogenesis
   Phosphatidylinositol 3-kinase
Integrin signalling pathway
   Phosphatidylinositol 3-kinase
Axon guidance mediated by netrin
   Phosphatidylinositol 3-kinase
Endothelin signaling pathway
   Phosphatidylinositol 3-kinase
PDGF signaling pathway
   Phosphatidylinositol 3-kinase
p53 pathway feedback loops 2
   Phosphatidylinositol 3-kinase
Gonadotropin-releasing hormone receptor pathway
   PI3K
CCKR signaling map
   p85
p53 pathway
   Phosphatidylinositol 3-kinase
GENE ONTOLOGY DATABASE ANNOTATIONS      Click to Expand...
GO MF Complete: kinase activator activity, insulin binding, protein phosphatase binding, phosphatidylinositol 3-kinase regulator activity, phosphatidylinositol 3-kinase regulatory subunit binding, ErbB-3 class receptor binding, insulin receptor binding, neurotrophin TRKA receptor binding, 1-phosphatidylinositol-3-kinase regulator activity, insulin-like growth factor receptor binding, phosphotyrosine residue binding, protein heterodimerization activity, insulin receptor substrate binding, kinase activity
GO BP Complete: insulin receptor signaling pathway, positive regulation of RNA splicing, positive regulation of filopodium assembly, transcription by RNA polymerase II, regulation of stress fiber assembly, extrinsic apoptotic signaling pathway via death domain receptors, positive regulation of transcription by RNA polymerase II, cellular response to insulin stimulus, positive regulation of smooth muscle cell proliferation, phosphatidylinositol 3-kinase/protein kinase B signal transduction, cytokine-mediated signaling pathway, negative regulation of osteoclast differentiation, cellular response to UV, positive regulation of tumor necrosis factor production, positive regulation of focal adhesion disassembly, myeloid leukocyte migration, interleukin-18-mediated signaling pathway, positive regulation of lamellipodium assembly, growth hormone receptor signaling pathway, regulation of protein localization to plasma membrane, positive regulation of protein import into nucleus, B cell differentiation, signal transduction, negative regulation of cell adhesion, regulation of toll-like receptor 4 signaling pathway, insulin-like growth factor receptor signaling pathway, intrinsic apoptotic signaling pathway in response to DNA damage, natural killer cell mediated cytotoxicity, positive regulation of endoplasmic reticulum unfolded protein response, osteoclast differentiation, positive regulation of leukocyte migration, negative regulation of stress fiber assembly, intracellular glucose homeostasis, negative regulation of cell-matrix adhesion, protein import into nucleus, negative regulation of apoptotic process, protein stabilization, response to endoplasmic reticulum stress
GO CC Complete: phosphatidylinositol 3-kinase complex, class IA, nucleus, cis-Golgi network, cell-cell junction, perinuclear region of cytoplasm, cytoplasm, perinuclear endoplasmic reticulum membrane, membrane, cytosol
REACTOME DATABASE ANNOTATIONS   Click to Expand...
Reactome Pathways: -

Orthologs