PANTHER Gene Information   
Gene Symbol(s): Gnb4
Organism: Mus musculus
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Gene Name: Guanine nucleotide-binding protein subunit beta-4
Gene ID: MGI:104581
Protein ID: P29387
Persistent Id: PTN000457551
Alternate Ids:
193436(GI) NM_001348062(refSeq)
14696(GeneID) BAE31054(EMBL-CDS)
Transducin beta chain 4(Synonym) ENSMUSP00000103869(Ensembl_PRO)
ENSMUST00000155737(Ensembl_TRS) M63658(EMBL)
Gnb4(Symbol) ENSMUSG00000027669(Ensembl)
GBB4_MOUSE(UniProtKB-ID) MGI:104581(MGI)
Q9JHX8(AltAccession)
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PANTHER Classification
PANTHER Family: GUANINE NUCLEOTIDE-BINDING PROTEIN BETA G PROTEIN BETA (PTHR19850)
PANTHER Subfamily: GUANINE NUCLEOTIDE-BINDING PROTEIN SUBUNIT BETA-4 (PTHR19850:SF28)  
PANTHER GO-slim Molecular Function: signaling receptor complex adaptor activity
PANTHER GO-slim Biological Process: G protein-coupled receptor signaling pathway
PANTHER GO-slim Cellular Component: plasma membrane protein complex
extrinsic component of membrane
cytoplasm
catalytic complex
cytoplasmic side of plasma membrane
PANTHER protein class: heterotrimeric G-protein
Pathway Categories: Beta3 adrenergic receptor signaling pathway
   G-Protein
Wnt signaling pathway
   G protein, beta subunit
Thyrotropin-releasing hormone receptor signaling pathway
   G-Protein
GABA-B receptor II signaling
   G protein, beta subunit
Histamine H1 receptor mediated signaling pathway
   G-Protein
5HT1 type receptor mediated signaling pathway
   G-protein
5HT4 type receptor mediated signaling pathway
   G-protein
Muscarinic acetylcholine receptor 1 and 3 signaling pathway
   Gq-protein
Dopamine receptor mediated signaling pathway
   G protein, beta subunit
Heterotrimeric G-protein signaling pathway-Gq alpha and Go alpha mediated pathway
   G protein-activated inward rectifying potassium channel
Gonadotropin-releasing hormone receptor pathway
   Gbeta
Heterotrimeric G-protein signaling pathway-Gi alpha and Gs alpha mediated pathway
   G protein, beta subunit
Endogenous cannabinoid signaling
   G protein, beta subunit
Beta1 adrenergic receptor signaling pathway
   G-Protein
PI3 kinase pathway
   G protein, beta and gamma subunit
5HT2 type receptor mediated signaling pathway
   G-protein
Enkephalin release
   Gi-protein
Opioid proenkephalin pathway
   G-protein
Enkephalin release
   Gs-protein
Angiotensin II-stimulated signaling through G proteins and beta-arrestin
   G-protein, beta subunit
Opioid prodynorphin pathway
   G-protein
Beta2 adrenergic receptor signaling pathway
   G-Protein
Histamine H2 receptor mediated signaling pathway
   G-Protein
Opioid proopiomelanocortin pathway
   G-protein
Muscarinic acetylcholine receptor 2 and 4 signaling pathway
   Gi-protein
Metabotropic glutamate receptor group III pathway
   Gi-protein
Heterotrimeric G-protein signaling pathway-rod outer segment phototransduction
   G protein, beta subunit
Cortocotropin releasing factor receptor signaling pathway
   G-Protein
Heterotrimeric G-protein signaling pathway-Gq alpha and Go alpha mediated pathway
   G protein beta subunit
Metabotropic glutamate receptor group II pathway
   G-protein
Oxytocin receptor mediated signaling pathway
   G-Protein
GENE ONTOLOGY DATABASE ANNOTATIONS      Click to Expand...
GO MF Complete: GTPase activity, signaling receptor complex adaptor activity, protein-containing complex binding
GO BP Complete: G protein-coupled receptor signaling pathway, signal transduction
GO CC Complete: heterotrimeric G-protein complex, myelin sheath, cytoplasm, cell body, synapse
REACTOME DATABASE ANNOTATIONS   Click to Expand...
Reactome Pathways: G protein gated Potassium channels, Regulation of insulin secretion, G alpha (q) signalling events, GPCR downstream signalling, Integration of energy metabolism, Vasopressin regulates renal water homeostasis via Aquaporins, Signaling by Nuclear Receptors, Inhibition of voltage gated Ca2+ channels via Gbeta/gamma subunits, Aquaporin-mediated transport, G-protein beta:gamma signalling, Protein folding, Thromboxane signalling through TP receptor, Adrenaline,noradrenaline inhibits insulin secretion, Presynaptic function of Kainate receptors, G beta:gamma signalling through PLC beta, Activation of kainate receptors upon glutamate binding, Glucagon-type ligand receptors, Opioid Signalling, Inwardly rectifying K+ channels, Signaling by WNT, G alpha (12/13) signalling events, Signal Transduction, Beta-catenin independent WNT signaling, Platelet homeostasis, Glucagon-like Peptide-1 (GLP1) regulates insulin secretion, GPER1 signaling, G beta:gamma signalling through BTK, Potassium Channels, G alpha (z) signalling events, GPCR ligand binding, Transport of small molecules, G alpha (i) signalling events, GABA receptor activation, Class B/2 (Secretin family receptors), G alpha (s) signalling events, GABA B receptor activation, Signal amplification, ADP signalling through P2Y purinoceptor 1, Transmission across Chemical Synapses, Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding, ESR-mediated signaling, Extra-nuclear estrogen signaling, Neuronal System, Chaperonin-mediated protein folding, Signaling by GPCR, Activation of G protein gated Potassium channels, Neurotransmitter receptors and postsynaptic signal transmission, G beta:gamma signalling through PI3Kgamma, ADP signalling through P2Y purinoceptor 12, Activation of GABAB receptors, Platelet activation, signaling and aggregation, Hemostasis, Thrombin signalling through proteinase activated receptors (PARs), Metabolism, G-protein activation, G beta:gamma signalling through CDC42, Prostacyclin signalling through prostacyclin receptor, Ca2+ pathway, Metabolism of proteins

Orthologs