PANTHER Gene Information   
Gene Symbol(s): Xpd
Organism: Drosophila melanogaster
View Gene in Tree
Tree Reduced Tree  
Tree Reduced Tree
Gene Name: General transcription and DNA repair factor IIH helicase subunit XPD
Gene ID: FBgn0261850
Protein ID: Q7KVP9
Persistent Id: PTN000158280
Alternate Ids:
37414(GeneID) FBpp0071503(Ensembl_PRO)
Q7KVP9_DROME(UniProtKB-ID) FBgn0261850(FlyBase)
45445340(GI) NP_726036(refSeq)
AAM70857(EMBL-CDS) FBgn0261850(Ensembl)
Q7KVP9(Synonym) AE013599(EMBL)
FBtr0071576(Ensembl_TRS)
Show All

PANTHER Classification
PANTHER Family: DNA REPAIR DEAD HELICASE RAD3/XP-D SUBFAMILY MEMBER (PTHR11472)
PANTHER Subfamily: GENERAL TRANSCRIPTION AND DNA REPAIR FACTOR IIH HELICASE SUBUNIT XPD (PTHR11472:SF1)  
PANTHER GO-slim Molecular Function: DNA helicase activity
damaged DNA binding
PANTHER GO-slim Biological Process: positive regulation of nucleobase-containing compound metabolic process
positive regulation of macromolecule metabolic process
transcription by RNA polymerase II
regulation of DNA recombination
PANTHER GO-slim Cellular Component: nucleus
PANTHER protein class: DNA helicase
Pathway Categories: No pathway information available
GENE ONTOLOGY DATABASE ANNOTATIONS      Click to Expand...
GO MF Complete: DNA binding, ATP binding, DNA helicase activity, hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides, damaged DNA binding, 5'-3' DNA helicase activity
GO BP Complete: regulation of chromosome segregation, RNA polymerase II promoter clearance, regulation of mitotic nuclear division, positive regulation of mitotic recombination, nucleotide-excision repair, transcription by RNA polymerase II, response to UV, DNA damage response, regulation of syncytial blastoderm mitotic cell cycle, transcription initiation at RNA polymerase II promoter, negative regulation of G2/M transition of mitotic cell cycle, transcription open complex formation at RNA polymerase II promoter
GO CC Complete: nucleus, polytene chromosome, polytene chromosome puff, polytene chromosome interband, cytoplasm, transcription factor TFIIH core complex, transcription factor TFIIH holo complex
REACTOME DATABASE ANNOTATIONS   Click to Expand...
Reactome Pathways: DNA Repair, RNA Polymerase I Promoter Escape, Formation of RNA Pol II elongation complex , RNA Polymerase II Transcription Elongation, RNA Polymerase I Promoter Clearance, TP53 Regulates Transcription of DNA Repair Genes, RNA Polymerase II Promoter Escape, RNA Polymerase II Transcription Initiation, RNA Pol II CTD phosphorylation and interaction with CE, RNA Polymerase II Transcription Initiation And Promoter Clearance, Gene expression (Transcription), mRNA Capping, Dual Incision in GG-NER, Formation of the Early Elongation Complex, RNA Polymerase II Transcription Pre-Initiation And Promoter Opening, RNA Polymerase II Transcription, Metabolism of RNA, Generic Transcription Pathway, RNA Polymerase I Transcription, Transcriptional Regulation by TP53, RNA Polymerase II Pre-transcription Events, Dual incision in TC-NER, Gap-filling DNA repair synthesis and ligation in TC-NER, Transcription-Coupled Nucleotide Excision Repair (TC-NER), Global Genome Nucleotide Excision Repair (GG-NER), Nucleotide Excision Repair, Formation of TC-NER Pre-Incision Complex, Formation of Incision Complex in GG-NER

Orthologs