PANTHER Gene Information   
Gene Symbol(s): RAD3
Organism: Saccharomyces cerevisiae
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Gene Name: General transcription and DNA repair factor IIH helicase subunit XPD
Gene ID: S000000973
Protein ID: P06839
Persistent Id: PTN000158285
Alternate Ids:
DNA repair helicase RAD3(Synonym) RAD3(Symbol)
X02368(EMBL) YER171W_mRNA(Ensembl_TRS)
YER171W(Ensembl) CAA26215(EMBL-CDS)
S000000973(SGD) 398365073(GI)
YEAST:G3O-30331-MON(BioCyc) 3.6.4.12(EC)
D3DM79(AltAccession) NM_001179061(refSeq)
856918(GeneID) RAD3_YEAST(UniProtKB-ID)
YER171W(Ensembl_PRO)
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PANTHER Classification
PANTHER Family: DNA REPAIR DEAD HELICASE RAD3/XP-D SUBFAMILY MEMBER (PTHR11472)
PANTHER Subfamily: GENERAL TRANSCRIPTION AND DNA REPAIR FACTOR IIH HELICASE SUBUNIT XPD (PTHR11472:SF1)  
PANTHER GO-slim Molecular Function: DNA helicase activity
damaged DNA binding
PANTHER GO-slim Biological Process: positive regulation of nucleobase-containing compound metabolic process
positive regulation of macromolecule metabolic process
transcription by RNA polymerase II
regulation of DNA recombination
PANTHER GO-slim Cellular Component: nucleus
PANTHER protein class: DNA helicase
Pathway Categories: No pathway information available
GENE ONTOLOGY DATABASE ANNOTATIONS      Click to Expand...
GO MF Complete: ATP hydrolysis activity, ATP-dependent activity, acting on DNA, double-stranded DNA helicase activity, hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides, helicase activity, four-way junction helicase activity, forked DNA-dependent helicase activity, cohesin loader activity, damaged DNA binding, 5'-3' DNA helicase activity, DNA binding, ATP binding, DNA helicase activity, DNA clamp loader activity, ATP-dependent H2AZ histone chaperone activity, metal ion binding, ATP-dependent H3-H4 histone complex chaperone activity, 4 iron, 4 sulfur cluster binding, single-stranded 3'-5' DNA helicase activity, chromatin extrusion motor activity, hydrolase activity, isomerase activity
GO BP Complete: DNA repair, chromatin remodeling, DNA duplex unwinding, positive regulation of mitotic recombination, regulation of mitotic recombination, nucleotide-excision repair, transcription by RNA polymerase II, chromatin looping, DNA damage response
GO CC Complete: nucleus, transcription factor TFIIH core complex, cytosol, transcription factor TFIIH holo complex, nucleotide-excision repair factor 3 complex
REACTOME DATABASE ANNOTATIONS   Click to Expand...
Reactome Pathways: Formation of TC-NER Pre-Incision Complex, DNA Repair, Nucleotide Excision Repair, RNA Polymerase II Transcription Initiation, RNA Polymerase I Transcription, RNA Polymerase I Promoter Clearance, RNA Polymerase II Transcription Elongation, Transcriptional Regulation by TP53, Dual incision in TC-NER, RNA Polymerase II Transcription, Gap-filling DNA repair synthesis and ligation in TC-NER, Generic Transcription Pathway, RNA Polymerase II Pre-transcription Events, RNA Polymerase II Transcription Pre-Initiation And Promoter Opening, TP53 Regulates Transcription of DNA Repair Genes, RNA Polymerase II Promoter Escape, RNA Pol II CTD phosphorylation and interaction with CE, Gene expression (Transcription), RNA Polymerase I Promoter Escape, RNA Polymerase II Transcription Initiation And Promoter Clearance, Transcription-Coupled Nucleotide Excision Repair (TC-NER), Metabolism of RNA, mRNA Capping, Formation of the Early Elongation Complex

Orthologs