PANTHER Gene Information   
Gene Symbol(s): ercc2
Organism: Xenopus tropicalis
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Gene Name: General transcription and DNA repair factor IIH helicase subunit XPD
Gene ID: XB-GENE-949792
Protein ID: Q66II2
Persistent Id: PTN008518659
Alternate Ids:
ENSXETP00000039540(Ensembl_PRO) ENSXETT00000039540(Ensembl_TRS)
82181185(GI) 493493(GeneID)
AAH81339(EMBL-CDS) ENSXETG00000018229(Ensembl)
Q66II2(Synonym) BC081339(EMBL)
Q66II2_XENTR(UniProtKB-ID) NP_001008131(refSeq)
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PANTHER Classification
PANTHER Family: DNA REPAIR DEAD HELICASE RAD3/XP-D SUBFAMILY MEMBER (PTHR11472)
PANTHER Subfamily: GENERAL TRANSCRIPTION AND DNA REPAIR FACTOR IIH HELICASE SUBUNIT XPD (PTHR11472:SF1)  
PANTHER GO-slim Molecular Function: DNA helicase activity
damaged DNA binding
PANTHER GO-slim Biological Process: positive regulation of nucleobase-containing compound metabolic process
positive regulation of macromolecule metabolic process
transcription by RNA polymerase II
regulation of DNA recombination
PANTHER GO-slim Cellular Component: nucleus
PANTHER protein class: DNA helicase
Pathway Categories: No pathway information available
GENE ONTOLOGY DATABASE ANNOTATIONS      Click to Expand...
GO MF Complete: double-stranded DNA helicase activity, hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides, helicase activity, four-way junction helicase activity, forked DNA-dependent helicase activity, damaged DNA binding, DNA binding, ATP binding, DNA helicase activity, metal ion binding, 4 iron, 4 sulfur cluster binding, single-stranded 3'-5' DNA helicase activity, hydrolase activity, isomerase activity
GO BP Complete: DNA repair, endodermal digestive tract morphogenesis, positive regulation of mitotic recombination, nucleotide-excision repair, transcription by RNA polymerase II, DNA damage response
GO CC Complete: nucleus
REACTOME DATABASE ANNOTATIONS   Click to Expand...
Reactome Pathways: RNA Pol II CTD phosphorylation and interaction with CE, Formation of RNA Pol II elongation complex , RNA Polymerase II Transcription Initiation And Promoter Clearance, Gap-filling DNA repair synthesis and ligation in TC-NER, Dual incision in TC-NER, Gene expression (Transcription), Formation of TC-NER Pre-Incision Complex, Transcription-Coupled Nucleotide Excision Repair (TC-NER), RNA Polymerase I Transcription, Generic Transcription Pathway, Global Genome Nucleotide Excision Repair (GG-NER), Nucleotide Excision Repair, RNA Polymerase I Transcription Termination, Formation of Incision Complex in GG-NER, Metabolism of RNA, RNA Polymerase II Transcription Pre-Initiation And Promoter Opening, Dual Incision in GG-NER, RNA Polymerase I Promoter Clearance, RNA Polymerase II Promoter Escape, RNA Polymerase II Transcription Elongation, RNA Polymerase II Transcription, Transcriptional Regulation by TP53, TP53 Regulates Transcription of DNA Repair Genes, RNA Polymerase II Pre-transcription Events, mRNA Capping, RNA Polymerase II Transcription Initiation, DNA Repair, RNA Polymerase I Promoter Escape

Orthologs