PANTHER Gene Information   
Gene Symbol(s): ERCC2
Organism: Felis catus
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Gene Name: General transcription and DNA repair factor IIH helicase subunit XPD
Gene ID: ENSFCAG00000002679.6
Protein ID: M3VYY5
Persistent Id: PTN001690250
Alternate Ids:
M3VYY5_FELCA(UniProtKB-ID) ENSFCAG00000002679(Ensembl)
AANG04000747(EMBL) ENSFCAP00000002466(Ensembl_PRO)
M3VYY5(Synonym) ENSFCAT00000002680(Ensembl_TRS)
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PANTHER Classification
PANTHER Family: DNA REPAIR DEAD HELICASE RAD3/XP-D SUBFAMILY MEMBER (PTHR11472)
PANTHER Subfamily: GENERAL TRANSCRIPTION AND DNA REPAIR FACTOR IIH HELICASE SUBUNIT XPD (PTHR11472:SF1)  
PANTHER GO-slim Molecular Function: DNA helicase activity
damaged DNA binding
PANTHER GO-slim Biological Process: positive regulation of nucleobase-containing compound metabolic process
positive regulation of macromolecule metabolic process
transcription by RNA polymerase II
regulation of DNA recombination
PANTHER GO-slim Cellular Component: nucleus
PANTHER protein class: DNA helicase
Pathway Categories: No pathway information available
GENE ONTOLOGY DATABASE ANNOTATIONS      Click to Expand...
GO MF Complete: double-stranded DNA helicase activity, hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides, helicase activity, four-way junction helicase activity, forked DNA-dependent helicase activity, damaged DNA binding, 5'-3' DNA helicase activity, DNA binding, ATP binding, DNA helicase activity, metal ion binding, 4 iron, 4 sulfur cluster binding, single-stranded 3'-5' DNA helicase activity, protein-macromolecule adaptor activity, hydrolase activity, isomerase activity
GO BP Complete: multicellular organism growth, embryonic cleavage, DNA repair, transcription elongation by RNA polymerase I, UV protection, determination of adult lifespan, transcription-coupled nucleotide-excision repair, post-embryonic development, nucleotide-excision repair, transcription by RNA polymerase II, chromosome segregation, response to UV, hair cycle process, skin development, transcription initiation at RNA polymerase II promoter, spinal cord development, erythrocyte maturation, maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA), response to oxidative stress, in utero embryonic development, DNA duplex unwinding, apoptotic process, central nervous system myelin formation, hair cell differentiation, bone mineralization, regulation of mitotic cell cycle phase transition, positive regulation of mitotic recombination, insulin-like growth factor receptor signaling pathway, hematopoietic stem cell differentiation, hair follicle maturation, DNA damage response, nucleobase-containing compound metabolic process, regulation of transcription by RNA polymerase II, intrinsic apoptotic signaling pathway by p53 class mediator, ribosomal small subunit biogenesis, extracellular matrix organization, hematopoietic stem cell proliferation
GO CC Complete: MMXD complex, nucleus, transcription factor TFIID complex, cytoplasm, transcription factor TFIIH core complex, spindle, cytosol, transcription factor TFIIH holo complex, CAK-ERCC2 complex, nucleoplasm
REACTOME DATABASE ANNOTATIONS   Click to Expand...
Reactome Pathways: -

Orthologs