PANTHER Gene Information   
Gene Symbol(s): hop-1
Organism: Caenorhabditis elegans
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Gene Name: Presenilin hop-1
Gene ID: WBGene00001985
Protein ID: O02100
Persistent Id: PTN000024488
Alternate Ids:
C18E3.8(Ensembl_TRS) AF021905(EMBL)
C18E3.8(Ensembl_PRO) hop-1(Symbol)
CE08317(WormBase_PRO) C18E3(WormBase_TRS)
HOP1_CAEEL(UniProtKB-ID) WBGene00001985(WormBase)
CCD65145(EMBL-CDS) NM_058927(refSeq)
2618987(GI) 172017(GeneID)
HOP1(Synonym) WBGene00001985(Ensembl)
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PANTHER Classification
PANTHER Family: PRESENILIN (PTHR10202)
PANTHER Subfamily: PRESENILIN HOP-1 (PTHR10202:SF14)  
PANTHER GO-slim Molecular Function: endopeptidase activity
PANTHER GO-slim Biological Process: membrane protein ectodomain proteolysis
peptide metabolic process
Notch signaling pathway
protein processing
calcium ion homeostasis
PANTHER GO-slim Cellular Component: catalytic complex
plasma membrane protein complex
PANTHER protein class: aspartic protease
Pathway Categories: Alzheimer disease-presenilin pathway
   Presenilin
Notch signaling pathway
   Presenilin
Alzheimer disease-presenilin pathway
   Presenilin N-terminal fragment
Alzheimer disease-presenilin pathway
   Presenilin C-terminal fragment

GO MF Complete: endopeptidase activity, aspartic endopeptidase activity, intramembrane cleaving
GO BP Complete: regulation of cell fate specification, calcium ion homeostasis, embryo development ending in birth or egg hatching, positive regulation of cell population proliferation, reproductive process, positive regulation of Notch signaling pathway, regulation of vulval development, Notch signaling pathway, gonad development, membrane protein ectodomain proteolysis, nematode larval development, egg-laying behavior, protein processing, amyloid-beta formation
GO CC Complete: endoplasmic reticulum membrane, membrane, gamma-secretase complex, Golgi membrane, endoplasmic reticulum, Golgi apparatus
Reactome Pathways: -