PANTHER Gene Information   
Gene Symbol(s): Pi3K21B
Organism: Drosophila melanogaster
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Gene Name: Pi3K21B, isoform B
Gene ID: FBgn0020622
Protein ID: Q7KTZ2
Persistent Id: PTN000016486
Alternate Ids:
33203(GeneID) NM_057922(refSeq)
FBpp0303632(Ensembl_PRO) FBgn0020622(FlyBase)
Q7KTZ2(Synonym) FBtr0331208(Ensembl_TRS)
AGB92354(EMBL-CDS) AE014134(EMBL)
440213064(GI) FBgn0020622(Ensembl)
Q7KTZ2_DROME(UniProtKB-ID)
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PANTHER Classification
PANTHER Family: PHOSPHATIDYLINOSITOL 3-KINASE REGULATORY SUBUNIT (PTHR10155)
PANTHER Subfamily: PI3K21B, ISOFORM B (PTHR10155:SF10)  
PANTHER GO-slim Molecular Function: kinase regulator activity
PANTHER GO-slim Biological Process: phosphatidylinositol phosphate biosynthetic process
PANTHER GO-slim Cellular Component: phosphatidylinositol 3-kinase complex
PANTHER protein class: kinase modulator
Pathway Categories: Integrin signalling pathway
   Phosphatidylinositol 3-kinase
VEGF signaling pathway
   Phosphatidylinositol 3-kinase
Endothelin signaling pathway
   Phosphatidylinositol 3-kinase
p53 pathway feedback loops 2
   Phosphatidylinositol 3-kinase
Insulin/IGF pathway-protein kinase B signaling cascade
   Phosphatidylinositol 3-kinase
Angiogenesis
   Phosphatidylinositol 3-kinase
p53 pathway
   Phosphatidylinositol 3-kinase
GENE ONTOLOGY DATABASE ANNOTATIONS      Click to Expand...
GO MF Complete: phosphotyrosine residue binding, phosphatidylinositol 3-kinase regulator activity, insulin receptor substrate binding, 1-phosphatidylinositol-3-kinase regulator activity, kinase binding
GO BP Complete: phosphatidylinositol 3-kinase/protein kinase B signal transduction, negative regulation of feeding behavior, insulin receptor signaling pathway, regulation of cell size, phosphatidylinositol phosphate biosynthetic process, positive regulation of lipid storage, regulation of cell population proliferation
GO CC Complete: phosphatidylinositol 3-kinase complex, class IA
REACTOME DATABASE ANNOTATIONS   Click to Expand...
Reactome Pathways: Fc epsilon receptor (FCERI) signaling, Signaling by VEGF, VEGFA-VEGFR2 Pathway, PI-3K cascade:FGFR2, Downstream signaling of activated FGFR2, Signaling by ERBB4, Signaling by ALK, MAPK family signaling cascades, Antigen activates B Cell Receptor (BCR) leading to generation of second messengers, Signal Transduction, Signaling by Receptor Tyrosine Kinases, Signaling by Interleukins, GAB1 signalosome, Signaling by FGFR1, Platelet activation, signaling and aggregation, Signaling by FGFR2, Signaling by PDGF, Signaling by Erythropoietin, Hemostasis, RAF/MAP kinase cascade, Interleukin-3, Interleukin-5 and GM-CSF signaling, PI3K Cascade, Innate Immune System, Erythropoietin activates Phosphoinositide-3-kinase (PI3K), PIP3 activates AKT signaling, Signaling by Rho GTPases, Miro GTPases and RHOBTB3, MAPK1/MAPK3 signaling, Negative regulation of the PI3K/AKT network, Signaling by Insulin receptor, Signaling by EGFR, Insulin receptor signalling cascade, Immune System, PI3K/AKT activation, PI-3K cascade:FGFR1, Intracellular signaling by second messengers, Developmental Biology, Downstream signaling of activated FGFR1, PI-3K cascade:FGFR4, RHO GTPase cycle, RHOD GTPase cycle, RHOG GTPase cycle, PI3K events in ERBB2 signaling, RAC2 GTPase cycle, Role of LAT2/NTAL/LAB on calcium mobilization, Signaling by NTRK1 (TRKA), Signaling by the B Cell Receptor (BCR), RHOJ GTPase cycle, Synthesis of PIPs at the plasma membrane, PI Metabolism, Signaling by Rho GTPases, Phospholipid metabolism, Signaling by NTRKs, PI-3K cascade:FGFR3, Signaling by FGFR, Regulation of signaling by CBL, GPVI-mediated activation cascade, Downstream signaling of activated FGFR4, Metabolism, IRS-related events triggered by IGF1R, RHOA GTPase cycle, IGF1R signaling cascade, Axon guidance, Signaling by Type 1 Insulin-like Growth Factor 1 Receptor (IGF1R), Signaling by FGFR4, Signaling by ERBB2, RHOU GTPase cycle, Signaling by FGFR3, Nervous system development, RHOB GTPase cycle, Adaptive Immune System, RHOF GTPase cycle, RET signaling, IRS-mediated signalling, Cytokine Signaling in Immune system, Downstream signaling of activated FGFR3, PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling, RHOV GTPase cycle, RAC1 GTPase cycle, RAC3 GTPase cycle, CDC42 GTPase cycle, Downstream signal transduction, PI3K events in ERBB4 signaling, Metabolism of lipids

Orthologs