PANTHER Gene Information   
Gene Symbol(s): kpc-1
Organism: Caenorhabditis elegans
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Gene Name: Furin-like protease kpc-1
Gene ID: WBGene00002232
Protein ID: O17798
Persistent Id: PTN000083053
Alternate Ids:
WBGene00002232(WormBase) FKPC1(Synonym)
F11A6.1a(Ensembl_PRO) F11A6.1a(WormBase_TRS)
CE17653(WormBase_PRO) 173051(GeneID)
BX284601(EMBL) 3875748(GI)
kpc-1{ECO:0000312|WormBase:F11A6.1a}(Symbol) O17797(AltAccession)
WBGene00002232(Ensembl) 3.4.21.- {ECO:0000305|PubMed:24671950}(EC)
FKPC1_CAEEL(UniProtKB-ID) AAB63525(EMBL-CDS)
F11A6.1a(Ensembl_TRS) NP_492974(refSeq)
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PANTHER Classification
PANTHER Family: PROPROTEIN CONVERTASE SUBTILISIN/KEXIN-RELATED (PTHR42884)
PANTHER Subfamily: FURIN-LIKE PROTEASE 1, ISOFORMS 1_1-X_2 (PTHR42884:SF3)  
PANTHER GO-slim Molecular Function: serine-type endopeptidase activity
PANTHER GO-slim Biological Process: protein processing
PANTHER GO-slim Cellular Component: trans-Golgi network
Golgi membrane
PANTHER protein class: serine protease
Pathway Categories: DPP signaling pathway
   furin 1
DPP-SCW signaling pathway
   furin 1
Activin beta signaling pathway
   furin 1
Endothelin signaling pathway
   Furin
SCW signaling pathway
   furin 1
MYO signaling pathway
   furin 1
BMP/activin signaling pathway-drosophila
   furin 1
GBB signaling pathway
   furin 1
Alzheimer disease-amyloid secretase pathway
   Furin
ALP23B signaling pathway
   furin 1
Alzheimer disease-presenilin pathway
   Furin

GO MF Complete: metal ion binding, serine-type endopeptidase activity, serine-type peptidase activity, signaling receptor binding
GO BP Complete: insulin processing, positive regulation of dendrite extension, protein localization to endosome, negative regulation of dauer entry, positive regulation of dendrite development, regulation of dendrite extension, positive regulation of synaptic assembly at neuromuscular junction, regulation of dendrite morphogenesis, dendrite morphogenesis, zymogen activation, negative regulation of protein localization to cell surface, dendrite self-avoidance, proteolysis, gene expression, peptide hormone processing, regulation of neuron migration, positive regulation of dendrite morphogenesis
GO CC Complete: trans-Golgi network, Golgi membrane, neuronal cell body, perikaryon, cell projection, plasma membrane, axon
Reactome Pathways: Activation of Matrix Metalloproteinases, Signal Transduction, Signaling by PDGF, Signaling by TGFB family members, RNA Polymerase II Transcription, SMAD2/SMAD3:SMAD4 heterotrimer regulates transcription, Transcriptional activity of SMAD2/SMAD3:SMAD4 heterotrimer, TGF-beta receptor signaling activates SMADs, Generic Transcription Pathway, Degradation of the extracellular matrix, Gene expression (Transcription), Signaling by Receptor Tyrosine Kinases, Signaling by TGF-beta Receptor Complex, Extracellular matrix organization