PANTHER Gene Information   
Gene Symbol(s): Vav
Organism: Drosophila melanogaster
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Gene Name: Protein vav
Gene ID: FBgn0040068
Protein ID: Q9NHV9
Persistent Id: PTN000518590
Alternate Ids:
AY069536(EMBL) 32920(GeneID)
A2RVJ3(AltAccession) Vav(Symbol)
AAF48943(EMBL-CDS) VAV_DROME(UniProtKB-ID)
22832552(GI) FBgn0040068(Ensembl)
FBgn0040068(FlyBase) VAV(Synonym)
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PANTHER Classification
PANTHER Family: PROTEIN VAV (PTHR45818)
PANTHER Subfamily: PROTEIN VAV (PTHR45818:SF3)  
PANTHER GO-slim Molecular Function: guanyl-nucleotide exchange factor activity
PANTHER GO-slim Biological Process: regulation of GTPase activity
PANTHER GO-slim Cellular Component: cytoplasm
PANTHER protein class:
Pathway Categories: PDGF signaling pathway
   Guanine nucleotide exchange factor VAV
GENE ONTOLOGY DATABASE ANNOTATIONS      Click to Expand...
GO MF Complete: guanyl-nucleotide exchange factor activity
GO BP Complete: dorsal closure, melanotic encapsulation of foreign target, small GTPase-mediated signal transduction, epidermal growth factor receptor signaling pathway, myoblast fusion, axon guidance, border follicle cell migration, negative regulation of epidermal growth factor receptor signaling pathway, open tracheal system development, vascular endothelial growth factor receptor signaling pathway, central nervous system development, regulation of actin cytoskeleton organization, photoreceptor cell axon guidance, compound eye morphogenesis, axonogenesis, positive regulation of ERK1 and ERK2 cascade, regulation of adherens junction organization, cell migration, actin cytoskeleton organization
GO CC Complete: cytoplasm, cytosol
REACTOME DATABASE ANNOTATIONS   Click to Expand...
Reactome Pathways: Drug ADME, FCERI mediated Ca+2 mobilization, Fc epsilon receptor (FCERI) signaling, VEGFA-VEGFR2 Pathway, Signaling by VEGF, Signal transduction by L1, Antigen activates B Cell Receptor (BCR) leading to generation of second messengers, Signal Transduction, Signaling by Receptor Tyrosine Kinases, Signaling by Interleukins, Azathioprine ADME, Platelet activation, signaling and aggregation, NRAGE signals death through JNK, Signaling by Erythropoietin, Hemostasis, Interleukin-3, Interleukin-5 and GM-CSF signaling, Innate Immune System, PIP3 activates AKT signaling, Signaling by Rho GTPases, Miro GTPases and RHOBTB3, VEGFR2 mediated vascular permeability, Negative regulation of the PI3K/AKT network, Immune System, Developmental Biology, Intracellular signaling by second messengers, RHO GTPase cycle, RHOG GTPase cycle, EPH-Ephrin signaling, Erythropoietin activates RAS, RAC2 GTPase cycle, GPCR downstream signalling, Signaling by the B Cell Receptor (BCR), FCERI mediated MAPK activation, DAP12 signaling, G alpha (12/13) signalling events, Signaling by Rho GTPases, p75 NTR receptor-mediated signalling, Signaling by SCF-KIT, Regulation of signaling by CBL, EPH-ephrin mediated repulsion of cells, GPVI-mediated activation cascade, RHOA GTPase cycle, Cell death signalling via NRAGE, NRIF and NADE, Axon guidance, Death Receptor Signaling, RHOB GTPase cycle, Adaptive Immune System, Nervous system development, Signaling by GPCR, L1CAM interactions, Cytokine Signaling in Immune system, PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling, DAP12 interactions, RAC1 GTPase cycle, RAC3 GTPase cycle, CDC42 GTPase cycle

Orthologs